Title: E6 Quiz
Course: Lab Instruments II > Section: E6: Meetings 14,15

This quiz covers the objectives for Experiment Set 6.

Q: Identify the correct order of stages in a mass spectrometer.
- Ionization, mass filtration, detection
- Ionization, detection, mass filtration
- Mass filtration, ionization, detection
- Mass filtration, detection, ionization
A: Ionization, mass filtration, detection

Q: Identify the FALSE statement regarding MS samples and analytes.
- The analytes are limited to atoms and small molecules.
- The samples can be in any state of matter for ionization.
- The samples are limited to pure/nearly pure substances.
- The analytes must be in the gaseous state for mass analysis.
A: The analytes are limited to atoms and small molecules.

Q: Which statement correctly describes soft ionization methods?
- High energy method
- Creates a fingerprint fragmentation pattern
- Molecular ion is commonly the base peak
- Causes a high degree of fragmentation of the molecular ion
A: Molecular ion is commonly the base peak

Q: Which one of the following is considered a hard ionization method?
- Chemical ionization
- Electron ionization
- Electrospray ionization
- Thermal ionization
A: Electron ionization

Q: Which ionization method is commonly used in LC-MS configurations?
- APCI
- CI
- EI
- TI
A: APCI

Q: Which of the follow correctly summarizes electrospray ionization?
- A vaporized sample is bombarded with electrons to form ions.
- An ionized reagent gas reacts with the analyte to produce ions.
- An aerosol of charged droplets undergoes solvent evaporation to release free ions.
- A liquid sample is nebulized and subjected to an electrical discharge source to create ions.
A: An aerosol of charged droplets undergoes solvent evaporation to release free ions.

Q: Which parameter is used to sort ions in a mass analyzer?
- Mass to charge ratio
- Mass to volume ratio
- Charge to diameter ratio
- Diameter to volume ratio
A: Mass to charge ratio

Q: Which type of mass analyzer sorts ions by timing the peak of spiral longitudinal paths with the detector slit?
- Sector mass analyzer
- Ion trap mass analyzer
- Quadrupole mass analyzer
- Time of flight mass analyzer
A: Quadrupole mass analyzer

Q: Which type of mass analyzer sorts ions by accelerating them through a bent tube in a magnetic or electric field?
- Sector mass analyzer
- Ion trap mass analyzer
- Quadrupole mass analyzer
- Time of flight mass analyzer
A: Sector mass analyzer

Q: Which of the following describes the typical stages in a MS/MS instrument.
- There is one ionization stage and two mass filtration stages.
- There is one ionization stage and three mass filtration stages.
- There are two ionization stages and one mass filtration stage.
- There are two ionization stages and two mass filtration stages.
A: There are two ionization stages and two mass filtration stages.

Q: Which statement is TRUE regarding a SIM chromatogram?
- It is produced by monitoring a wide range of m/z values.
- A peak represents all the ions generated for the substance.
- Each peak is associated with a complete mass spectrum of the component.
- Not all components eluting from the column may have a representative peak.
A: Not all components eluting from the column may have a representative peak.

Q: Which of the following is a component utilized by non-tandem TOF instruments to narrow bandwidths for high molecular weight ions?
- Collision cell
- Dynode
- Ion trap
- Reflectron
A: Reflectron

Q: Which of the following is utilized to intensify the signal produced by an analyte ion in an electron multiplier mass detector?
- Collision cell
- Dynode
- Ion trap
- Ion trap
A: Dynode

Q: Which of the following peaks represents the mass of the analyte itself?
- Base peak
- Isotope peak
- Fragment peak
- Molecular ion peak
A: Molecular ion peak

Q: Which of the following peaks is relatively small in the mass spectra produced in any type of instrument?
- Base peak
- Isotope peak
- Fragment peak
- Molecular ion peak
A: Isotope peak