Title: Module 9 Endocrine and Hematologic Disorders
Course: DEH 2400 Oral Pathology > Section: Module 9 Endocrine and Hematologic Disorders

Introduction

It is imperative that the dental hygienist has a understanding of how oral health and systemic health are related. Diseases of the oral cavity can affect systemic health and systemic diseases can have an effect on oral health. This module includes the clinical features, oral manifestations, and the diagnosis and treatment of endocrine and hematologic disorders.
The dental hygienist should be knowledgeable of the oral manifestations of systemic disease and how oral health affects systemic diseases.

Objectives

After completing this module the student will be able to:

- Describe the difference between gigantism and acromegaly and list the physical characteristics of each.
- State the oral manifestations of hyperthyroidism.
- Describe the difference between primary and secondary hyperparathyroidism.
- List the oral and systemic manifestations that occur in the uncontrolled diabetic state.
- List the major clinical characteristics of type 1 and type 2 diabetes.
- Define Addison disease and describe the changes that occur on the skin and oral mucosa in a patient with Addison disease.
- Compare and contrast the cause, laboratory findings, and oral manifestations of each of the following: iron deficiency anemia, pernicious anemia, folic acid deficiency, and vitamin B deficiency.
- Compare and contrast the definitions and oral manifestations of thalassemia major and sickle cell anemia.
- Define celiac sprue.
- Describe the difference between primary and secondary aplastic anemia.
- Describe the oral manifestations of polycythemia.
- Explain why platelets may be deficient in polycythemia vera.
- Describe the most characteristic oral manifestations of agranulocytosis.
- Describe and contrast acute and chronic leukemia.
- Describe the oral manifestations of thrombocytopenia and nonthrombocytopenic purpura.
- Define hemophilia and describe its oral manifestations and treatment.

Reading and Resources

Textbook: Oral Manifestations of Systemic Diseases pp. 288-319
Video: Diabetes Basics: What is Diabetes? http://www.youtube.com/watch?v=MHlWM8_iqfA
Video: Obesity and Type 2 Diabetes http://www.youtube.com/watch?v=YoPyFGYcr7s
Video: Your Guide To von Willebrand Disease http://www.nhlbi.nih.gov/health/public/blood/vwd_in_brief.pdf
Video: Sickle Cell Disease Education and Awareness in Your Community http://www.youtube.com/watch?v=gnrvYsZWR1c