Title: Quiz 3
Course: DEH 2400 Oral Pathology > Section: Module 3 Immunology

Q: The eye damage that occurs in Sjögren syndrome is called:
- xerophthalmia.
- keratoconjunctivitis sicca.
- conjunctivitis.
- burning eyes.
A: keratoconjunctivitis sicca.

Q: Diagnosis of systemic lupus erythematosus (SLE) is made on the basis of:
- skin lesions.
- multiorgan involvement and the presence of anti-nuclear antibodies in the serum.
- arthritis and arthralgia.
- shortness of breath.
A: multiorgan involvement and the presence of anti-nuclear antibodies in the serum.

Q: The most common oral manifestation of Sjögren syndrome is:
- xerostomia.
- xerophthalmia.
- epimyoepithelial islands.
- aphthous ulcers.
A: xerostomia.

Q: Primary Sjögren syndrome occurs when:
- another autoimmune disease accompanies salivary and lacrimal gland involvement.
- there is only salivary and lacrimal gland involvement without the presence of another autoimmune disease.
- rheumatoid arthritis is present.
- Raynaud phenomenon is present.
A: there is only salivary and lacrimal gland involvement without the presence of another autoimmune disease.

Q: Which one of the following is not a characteristic feature of pemphigus vulgaris?
- Epithelial acantholysis
- Bullae
- Tzanck cells
- Occurrence most commonly in females
A: Occurrence most commonly in females

Q: Treatment for pemphigus vulgaris involves:
- high doses of systemic corticosteroids.
- antihistamines.
- antibiotics.
- antiviral drugs.
A: high doses of systemic corticosteroids.

Q: The most characteristic skin lesion in SLE is described as:
- a blister.
- urticaria.
- a butterfly rash.
- a bulla.
A: a butterfly rash.

Q: The histologic appearance of lesions in SLE may resemble:
- an ulcer.
- lichen planus.
- pemphigus vulgaris.
- erythema multiforme.
A: lichen planus.

Q: Pemphigus vulgaris differs histologically from cicatricial pemphigoid in that pemphigus vulgaris involves:
- degeneration of the epithelium.
- connective tissue fragmentation.
- significant numbers of inflammatory cells.
- scarring.
A: degeneration of the epithelium.

Q: The diagnosis of Behçet syndrome requires which of the following?
- Two of the three principal manifestations
- The presence of all three manifestations
- A biopsy
- A history of pemphigus vulgaris
A: Two of the three principal manifestations

Q: The most common oral site for cicatricial pemphigoid is the:
- floor of the mouth.
- gingiva.
- palate.
- tongue.
A: gingiva.

Q: The diagnosis of cicatricial pemphigoid is made on the basis of:
- the clinical appearance of the lesions.
- Nikolsky sign.
- biopsy and histologic examination.
- response to corticosteroids.
A: biopsy and histologic examination.

Q: The onset of this condition is explosive. It is characterized by skin and mucosal lesions. The skin lesions are referred to as target, iris, or bull’s eye lesions. The mucosal lesions affect the buccal mucosa, lips, and tongue and appear as superficial ulcerations. The lip lesions are ulcerated, encrusted, and bloody.

On the basis of this description, you suspect:
- lichen planus.
- erythema multiforme.
- contact dermatitis.
- SLE.
A: erythema multiforme.

Q: This patient has Sjögren syndrome and severe xerostomia.

Which clinical feature most appropriately describes the changes on the tongue in this patient?
- Dryness
- Candidiasis
- Loss of filiform and fungiform papillae
- Fissures
A: Loss of filiform and fungiform papillae

Q: The classic appearance of what condition shown below is a pattern of interconnecting slender lines referred to as Wickham striae?
- Lichen planus
- Linea alba
- Erythema multiforme
- Reiter syndrome
A: Lichen planus