Title: Quiz 6
Course: DEH 2400 Oral Pathology > Section: Module 6 Genetics

Q: Which of the following statements is correct concerning chromosomes?
- They are located in the cytoplasm of the cell.
- Mature germ cells (ova and spermatozoa) contain 46 chromosomes.
- Chromosomes can only be seen clearly under a microscope when the nucleus and cell are dividing.
- Chromosomes contain RNA, which directs the production of amino acids, polypeptides, and proteins by the cell.
A: Chromosomes can only be seen clearly under a microscope when the nucleus and cell are dividing.

Q: Primitive germ cells have _____ chromosomes and are called _____.
- 23; diploid
- 46; haploid
- 23; haploid
- 46; diploid
A: 46; diploid

Q: Points of contact between the chromatid of one chromosome and the chromatid of the other chromosome of a pair, where crossing over and exchange of chromosome segments occur, are called:
- first meiosis.
- second meiosis.
- chiasmata.
- interpolation.
A: chiasmata.

Q: The gap 2 (G_2) phase of mitosis:
- begins when mitotic division ends.
- ends when mitotic division begins.
- precedes the S phase.
- is when replication of DNA takes place.
A: ends when mitotic division begins.

Q: The correct order for the stages of mitosis is:
- prophase, anaphase, metaphase, telophase.
- prophase, metaphase, anaphase, telophase.
- prophase, metaphase, telophase, anaphase.
- metaphase, prophase, telophase, anaphase.
A: prophase, metaphase, anaphase, telophase.

Q: Most cases of Down syndrome are associated with:
- maternal consumption of alcohol.
- late maternal age at the time of conception.
- estrogen supplements.
- inhalation of vapors from volatile substances.
A: late maternal age at the time of conception.

Q: Which of the following statements is true regarding gross chromosomal abnormalities involving alterations in the number of human chromosomes?
- Aneuploidy is a complete second set of chromosomes, meaning a total of 46.
- Polyploidy is any number of chromosomes that do not represent an exact multiple of the total chromosome complement.
- Euploidy is a complete second set of chromosomes, meaning a total of 46.
- Aneuploidy may be represented by trisomy and monosomy.
A: Aneuploidy may be represented by trisomy and monosomy.

Q: Which is true about making a karyotype?
- Arginine may be used to arrest the mitosis of leukocytes at metaphase.
- Colchicine may be used to arrest the mitosis of leukocytes at metaphase.
- Colchicine may be used to arrest the mitosis of red blood cells at anaphase.
- It is used to evaluate molecular abnormalities in chromosomes.
A: Colchicine may be used to arrest the mitosis of leukocytes at metaphase.

Q: If both loci for blood are AO, the
- person is said to have blood group O.
- person is said to have blood group A.
- person would be homozygous.
- characteristic is recessive.
A: person is said to have blood group A.

Q: A man’s X chromosome is transmitted to _____ of his daughters and _____ of his sons.
- none; none
- none; all
- all; none
- all; all
A: all; none

Q: For autosomal-dominant inheritance:
- males will be affected more often than females.
- the risk of having an affected offspring is 25% when a person has a gene for the condition.
- all of the offspring will be affected by a condition that is transmitted by autosomal-dominant inheritance.
- an individual can carry a gene with a dominant effect without presenting any clinical manifestations.
A: an individual can carry a gene with a dominant effect without presenting any clinical manifestations.

Q: The majority of patients with Turner syndrome have a _____ phenotype and _____ chromosomes.
- male; 47
- female; 46
- female; 45
- male; 44
A: female; 45

Q: Do you accept all the items in the syllabus?
- Yes
- No
A: Yes

Q: Which of the following clinical syndromes caused by gross chromosomal abnormalities is associated with bilateral cleft lip and palate, microphthalmia or anophthalmia, and polydactyly?
- Trisomy 13
- Trisomy 21
- Turner syndrome
- Klinefelter syndrome
A: Trisomy 13

Q: Have you read the syllabus completely and thoroughly?
- Yes
- No
A: Yes