Title: Quiz 7
Course: DEH 2400 Oral Pathology > Section: Module 7 Neoplasia

Q: An intraoral mucosal lesion that shows a mixture of red and white areas is generally called:
- erythroplakia.
- speckled erythroplakia.
- speckled leukoplakia.
- leukoplakia.
A: speckled leukoplakia.

Q: Idiopathic leukoplakia:
- is a malignant lesion of the oral mucosa.
- can be rubbed off with gauze squares.
- is caused by direct irritation, as in tobacco pouch keratosis.
- does not have a specific known cause.
A: does not have a specific known cause.

Q: Which of the following statements about epithelial dysplasia is true?
- It is considered a malignant condition.
- Unlike squamous cell carcinoma, cellular changes in epithelial dysplasia may revert to normal if the stimulus, such as tobacco smoking, is removed.
- It presents clinically as an erythematous lesion and not a white lesion (leukoplakia).
- Lesions often arise on the hard and soft palate.
A: Unlike squamous cell carcinoma, cellular changes in epithelial dysplasia may revert to normal if the stimulus, such as tobacco smoking, is removed.

Q: Which of the following statements about erythroplakia is true?
- Most cases of erythroplakia occur on the buccal mucosa and vestibule.
- Erythroplakia is more common than leukoplakia.
- When examined microscopically, 90% of cases of erythroplakia demonstrate epithelial dysplasia or squamous cell carcinoma.
- Erythroplakia is considered a less serious clinical finding than leukoplakia.
A: When examined microscopically, 90% of cases of erythroplakia demonstrate epithelial dysplasia or squamous cell carcinoma.

Q: Squamous cell carcinoma of the oral epithelium usually metastasizes first to the:
- spleen.
- lungs.
- liver.
- lymph nodes.
A: lymph nodes.

Q: Severe epithelial dysplasia involving the full thickness of the epithelium is called:
- anaplasia.
- squamous cell carcinoma.
- carcinoma in situ.
- metastasis.
A: carcinoma in situ.

Q: Squamous cell carcinomas on the vermilion border of the lips and skin of the face are:
- associated with lack of exposure to the sun and vitamin D deficiency.
- more common in individuals with dark skin.
- associated with a poorer prognosis than that for squamous cell carcinoma of the oral mucosa.
- associated with color changes of the vermilion border from dark pink and uniform to mottled grayish pink.
A: associated with color changes of the vermilion border from dark pink and uniform to mottled grayish pink.

Q: “Keratin pearls” are a characteristic feature of:
- squamous cell carcinoma.
- basal cell carcinoma.
- pleomorphic adenoma.
- monomorphic adenoma.
A: squamous cell carcinoma.

Q: According to the TNM staging system for oral squamous carcinoma, T_2, N_1, M_0 would mean tumor _____ cm in diameter, _____ palpable nodes, and _____ metastasis.
- less than 2; ipsilateral; no distant
- 2 to 4; ipsilateral; no distant
- 2 to 4; contralateral; no distant
- 2 to 4; contralateral; distant
A: 2 to 4; ipsilateral; no distant

Q: Which of the following choices is not regarded as an initiating factor in the development of oral cancer?
- Cigar, pipe, and cigarette smoking
- Snuff dipping and tobacco chewing
- Consumption of alcohol
- Chronic irritation
A: Chronic irritation

Q: Most cases of verrucous carcinoma occur in the _____ years old.
- posterior lateral border of the tongue of women over 40
- floor of the mouth of women over 70
- vestibule and buccal mucosa of men over 55
- bone of the mandible of men over 20
A: vestibule and buccal mucosa of men over 55

Q: Verrucous carcinoma:
- has a better prognosis than other forms of squamous cell carcinomas.
- appears clinically as a quick-growing exophytic tumor with a pebbly white surface.
- is characterized by poorly differentiated epithelium with atypical cells.
- shows invasion of tumor cells through the basement membrane.
A: has a better prognosis than other forms of squamous cell carcinomas.

Q: As a general rule, a patient should be referred to an oral and maxillofacial surgeon or dermatologist to have a biopsy performed on any nonhealing ulcer of the skin or lips that has been present for more than:
- twenty-four hours.
- ten days.
- three months.
- one year.
A: ten days.

Q: Basal cell carcinoma is a _____ tumor that _____ in the oral cavity.
- benign; occurs
- malignant; occurs
- benign; does not occur
- malignant; does not occur
A: malignant; does not occur

Q: A benign tumor of salivary gland origin is called a(n):
- leiomyoma.
- lipoma.
- adenoma.
- papilloma.
A: adenoma.